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Progestin Exemestane

Country/Region china
Company WELLGREEN TECHNOLOGY CO.,LTD
Categories Female Sex Hormones
Telephone +86-29-88453375,89388326
ICP License Issued by the Chinese Ministry
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Progestin Exemestane

Description

Equipped with the best GMP factory of best quality exemestane for cosmetic, health care and human nutritional products in China, it is able to supply you with top quality exemestane USP/EP 99%, as well as the reactive intermediate of natural food supplements products.

Product Description

Many breast cancers are stimulated to grow by the female sex hormones oestrogen and progesterone. These breast cancers are called hormone sensitive or hormone receptor positive and can be treated with drugs that block the effects of these hormones.

In women who have had their menopause, oestrogen is mainly produced by changing androgens (sex hormones produced by the adrenal glands) into oestrogens. This process is called aromatisation and happens mainly in the fatty tissues, muscle and the skin. It needs a particular enzyme called aromatase.

Exemestane blocks the process of aromatisation. So it lowers the amount of oestrogen in the body. In early breast cancer, taking exemestane can help to stop breast cancer coming back. In advanced breast cancer the cancer cells may grow more slowly or stop growing completely.

CAS NO.: 107868-30-4

Molecular Formula: C20H24O2

Molecular Weight: 296.4034

Melting Point: 155.13℃

Specification: USP

Item

Spec.

Characteristics

White Crystalline Power

Identification

A: IR

B: RT(HPLC)

Residue on Ignition

≤0.1%

Heavy Metals

≤10ppm

Water

≤0.5%

Specific Optical Rotation

+290~+300°

Impurity


Spirooxiran 1

≤0.15%

Spirooxiran 2

≤0.15%

Exemestane related

Compound C

≤0.15%

Exemestane related

Compound A

≤0.15%

Any unspecified impurity

≤0.10%

Total impurity

≤0.50%

Assay (HPLC)

98.0%~102.0%

Micron


Conclusion

USP Pending Monograph, Conform the stipulation

Application

This product is a second generation aromatase inhibitors, used in the treatment of metastatic breast cancer and is used as the adjuvant treatment of early breast cancer.

Packing &Delivery

Packaging Detail:1kg/Alu-bag; 25kg/Drum

Delivery Detail:Immediately

Storage and Shelf Life

Store in cool & dry place, Keep away from strong light and heat, 24 months when properly stored

Quality Progestin Exemestane for sale
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